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cosalane MeSH Supplementary Concept Data 2024


MeSH Supplementary
cosalane
Unique ID
C083060
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C083060
Entry Term(s)
NSC 658586
NSC-658586
Pharm Action
Anti-HIV Agents
Registry Number
2R84Y6217J
Related Numbers
154212-56-3
CAS Type 1 Name
Benzoic acid, 3,3'-(4-((3beta,5alpha)-cholestan-3-yl)-1-buten-1-ylidene)bis(5-chloro-6-hydroxy)-
Heading Mapped to
Aurintricarboxylic Acid / *analogs & derivatives
Frequency
25
Note
active against a variety of HIV-1 strains & against HIV-2; inhibits the binding of gp120 to CD4 cells & of the postbinding events that lead to fusion of the virus with the cell membrane
Source
Lancet 1993 Sep 18;342(8873):733
Date of Entry
1993/10/05
Revision Date
2017/08/25
cosalane Preferred
NSC 658586 Narrower
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