MeSH Browser

MeSH Supplementary: 5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate
Unique ID: C083567
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C083567
Entry Term(s): 5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate, (2S-cis)-isomer; FTCTP
Registry Number: 145819-92-7
Related Numbers: 145919-60-4
Heading Mapped to: Cytidine Triphosphate / *analogs & derivatives; *Thiophenes
Frequency: 3
Note: inhibits the production of full-length minus strand DNA in an endogenous reverse transcriptase reaction; is also used as a chain terminator substrate; RN refers to (2R-cis)-isomer
Source: Antimicrob Agents Chemother 1993 Aug;37(8):1720-2
Indexing Information: HIV Reverse Transcriptase
Date of Entry: 1993/11/04
Revision Date: 2007/08/13

5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate MeSH Supplementary Concept Data 2024