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5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate
MeSH Supplementary Concept Data 2025
Details
Concepts
MeSH Supplementary
5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate
Unique ID
C083567
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C083567
Entry Term(s)
5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate, (2S-cis)-isomer
FTCTP
Registry Numbers
145819-92-7
145919-60-4
Related Numbers
145919-60-4
Heading Mapped to
Cytidine Triphosphate
/
analogs & derivatives
*Thiophenes
Frequency
3
Note
inhibits the production of full-length minus strand
DNA
in an endogenous reverse transcriptase reaction; is also used as a chain terminator substrate; RN refers to (2R-cis)-isomer
Source
Antimicrob Agents Chemother 1993 Aug;37(8):1720-2
Indexing Information
HIV Reverse Transcriptase
Date of Entry
1993/11/04
Revision Date
2007/08/13
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5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate
Preferred
Concept UI
M0222281
Registry Numbers
145819-92-7
Related Numbers
145919-60-4
Terms
5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate
Preferred Term
Term UI
T252286
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (1993)
FTCTP
Term UI
T252285
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (1993)
5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate, (2S-cis)-isomer
Narrower
Concept UI
M0326315
Registry Numbers
145919-60-4
Terms
5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate, (2S-cis)-isomer
Preferred Term
Term UI
T356315
Date
08/18/1999
LexicalTag
NON
ThesaurusID
NLM (1993)
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