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R 86183 MeSH Supplementary Concept Data 2024


MeSH Supplementary
R 86183
Unique ID
C086147
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C086147
Entry Term(s)
R-86183
R86183
Registry Number
0
Heading Mapped to
*Benzodiazepines
*Imidazoles
Frequency
7
Note
a derivative of TIBO (tetrahydroimidazo(4,5,1-jk)(1,4)-benzodiazepin-2(1H)-thione); differs from R82193 only in the positioning of a single chlorine molecule; not active against murine retrovirus but is 10-fold more potent than R82193 in inhibiting HIV-1 replication
Source
AIDS Res Hum Retroviruses 1993 Nov;9(11):1097-106
Indexing Information
HIV Reverse Transcriptase
Date of Entry
1994/04/06
Revision Date
2007/08/13
R 86183 Preferred
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