MeSH Browser

MeSH Supplementary: G120R protein, human
Unique ID: C093172
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C093172
Entry Term(s): (G120R)hGH protein, human; growth hormone G120R, human; hGH-G120R protein, human
Registry Number: 0
Heading Mapped to: *Recombinant Proteins; Growth Hormone / *analogs & derivatives
Frequency: 12
Note: a human growth hormone antagonist; results from the substitution of arginine for glycine at position 120 in native 22-kDa human growth hormone; shows somatotropin Zn-dependent agonist and antagonist activity on Nb2 cells; acts as a competitive antagonist to human growth hormone (GH) due to deficient site binding of the GH receptor
Source: J Biol Chem 1995 Apr 21;270(16):9222-6
Date of Entry: 1995/05/22
Revision Date: 2005/08/17

G120R protein, human MeSH Supplementary Concept Data 2024