MeSH Browser

MeSH Supplementary: F 4614
Unique ID: C097260
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C097260
Entry Term(s): F-4614; F4614
Registry Numbers: 0
Heading Mapped to: *Tumor Necrosis Factor-alpha
Frequency: 4
Note: a mutein of tumor necrosis factor alpha (TNF-alpha); contains mutations of Thr(5) substituted by Gly, Pro(6) substituted by Asp, and Arg(29) substituted by Val; the mutations resulted in cell-adhesive Arg-Gly-Asp and reduced hypotensive effects and lower lethality
Source: J Interferon Cytokine Res 1995 Aug;15(8):677-84
Date of Entry: 1996/01/25
Revision Date: 2001/05/22

F 4614 MeSH Supplementary Concept Data 2025