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F 4614 MeSH Supplementary Concept Data 2025


MeSH Supplementary
F 4614
Unique ID
C097260
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C097260
Entry Term(s)
F-4614
F4614
Registry Numbers
0
Heading Mapped to
*Tumor Necrosis Factor-alpha
Frequency
4
Note
a mutein of tumor necrosis factor alpha (TNF-alpha); contains mutations of Thr(5) substituted by Gly, Pro(6) substituted by Asp, and Arg(29) substituted by Val; the mutations resulted in cell-adhesive Arg-Gly-Asp and reduced hypotensive effects and lower lethality
Source
J Interferon Cytokine Res 1995 Aug;15(8):677-84
Date of Entry
1996/01/25
Revision Date
2001/05/22
F 4614 Preferred
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