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clasto-lactacystin beta-lactone MeSH Supplementary Concept Data 2025


MeSH Supplementary
clasto-lactacystin beta-lactone
Unique ID
C098869
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C098869
Entry Term(s)
c-lact compound
clasto-lactacystin beta-lactone, (1R-(1alpha(S*),4beta,5alpha))-isomer
Pharm Action
Cysteine Proteinase Inhibitors
Registry Numbers
155975-72-7
154226-60-5
Related Numbers
154226-60-5
Heading Mapped to
*Lactones
Frequency
63
Note
active metabolite of lactacystin; inhibits 20 S proteasome; structure in first source
Source
J Biol Chem 1996 Mar 29;271(13):7273-6
Date of Entry
1996/05/06
Revision Date
2007/02/26
clasto-lactacystin beta-lactone Preferred
clasto-lactacystin beta-lactone, (1R-(1alpha(S*),4beta,5alpha))-isomer Narrower
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