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6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one
MeSH Supplementary Concept Data 2025
Details
Concepts
MeSH Supplementary
6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one
Unique ID
C106647
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C106647
Entry Term(s)
TAS 103
TAS-103
TAS-103 free base
Pharm Action
Topoisomerase I Inhibitors
Topoisomerase II Inhibitors
Registry Numbers
YVC96489QV
1X260YUP2P
Related Numbers
1X260YUP2P
CAS Type 1 Name
7H-Indeno(2,1-c)quinolin-7-one, 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-
Heading Mapped to
*Aminoquinolines
*Indenes
Frequency
28
Note
inhibits topoisomerase I and topoisomerase II; structure in first source
Source
J Chromatogr B Biomed Appl 1997 Mar 28;691(1):179-85
Date of Entry
1997/07/15
Revision Date
2017/08/15
Expand All
Collapse All
6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one
Preferred
Concept UI
M0277786
Registry Numbers
YVC96489QV
Related Numbers
1X260YUP2P
Terms
6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one
Preferred Term
Term UI
T307791
Date
01/01/1955
LexicalTag
NON
ThesaurusID
NLM (1997)
TAS-103 free base
Term UI
T000930101
Date
08/15/2017
LexicalTag
NON
ThesaurusID
FDA SRS (2017)
TAS 103
Narrower
Concept UI
M0277788
Registry Numbers
1X260YUP2P
Terms
TAS 103
Preferred Term
Term UI
T307793
Date
01/01/1955
LexicalTag
LAB
ThesaurusID
NLM (1997)
TAS-103
Term UI
T307792
Date
01/01/1955
LexicalTag
LAB
ThesaurusID
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