MeSH Browser

MeSH Supplementary: telithromycin
Unique ID: C106791
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C106791
Entry Term(s): HMR 3647; HMR-3647; HMR3647; Ketek; RU 66647; RU-66647
Pharm Action: Anti-Bacterial Agents
Registry Number: KI8H7H19WL
Previous Indexing: *MACROLIDES (1997-2004)
Heading Mapped to: *Ketolides
Frequency: 607
Note: a ketolide; semisynthetic derivative of erythromycin with cycling of the C11-12 positions to form a carbamate ring to avoid acquired resistance to macrolides; binds 70S bacterial rRNA, specifically to the 23S part (23S RIBOSOMAL RNA), preventing protein synthesis;
Source: Diagn Microbiol Infect Dis 1997 Jan-Feb;27(1-2):7-12; The Annals of Pharmacotherapy 2002 36:452-64
Indexing Information: Protein Synthesis Inhibitors; RNA, Ribosomal, 23S
Date of Entry: 1997/07/22
Revision Date: 2016/08/18

telithromycin MeSH Supplementary Concept Data 2024