MeSH Browser

MeSH Supplementary: 2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide
Unique ID: C115284
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C115284
Entry Term(s): 2-cyano-3-hydroxy-N-(4--(trifluoromethyl)phenyl)-2-hepten-6-ynoic acid; FK 778; FK-778; FK778; HMR 1715; HMR-1715; MNA 715; MNA-715; MNA-X 920715; X 920715; X-920715; malononitrilamide 715; malononitrilamide-715
Registry Numbers: 185915-33-7; 0
Related Numbers: 4B135RK2KL
Heading Mapped to: *Alkynes; *Isoxazoles; *Nitriles
Frequency: 104
Note: structure in first source; a derivative of A77 1726, the active metabolite of the antirheumatic drug leflunomide, where the isoxazole ring has opened to become a nitrile and an alkyne
Source: Rapid Commun Mass Spectrom. 2005;19(18):2681-8; Scand J Immunol 1998 Oct;48(4):379-88
Date of Entry: 1998/11/12
Revision Date: 2018/11/16

2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide MeSH Supplementary Concept Data 2025