Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

insulin-cleaving membrane proteinase MeSH Supplementary Concept Data 2025


MeSH Supplementary
insulin-cleaving membrane proteinase
Unique ID
C121424
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C121424
Entry Term(s)
ICMP enzyme
Registry Numbers
EC 3.4.24.-
Heading Mapped to
*Metalloendopeptidases
Frequency
2
Note
membrane proteinase from Pseudomonas aeruginosa cleaves Glu(13)-Ala(14) and Tyr(16)-Leu(17) of insulin B-chain; Phe(25)-Tyr(26) and His(10)-Leu(11) are secondary cleavage sites; partial amino acid sequence in first source
Source
Biochim Biophys Acta 1999 Aug 30;1454(3):236-50
Date of Entry
1999/09/30
Revision Date
2001/03/26
insulin-cleaving membrane proteinase Preferred
page delivered in 0.007s