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TEL-ARG fusion protein, human MeSH Supplementary Concept Data 2025


MeSH Supplementary
TEL-ARG fusion protein, human
Unique ID
C426235
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C426235
Entry Term(s)
TEL-ARG protein, human
Registry Numbers
0
Heading Mapped to
*Recombinant Fusion Proteins
*Oncogene Proteins, Fusion
Frequency
4
Note
human fusion protein reported in patients with chronic myeloid leukemia was engineered and expressed in mice; formed by t(1;12)(q25;p13) reciprocal translocation, which fuses part of the TEL gene to the tyrosine kinase; TEL/ARG-transfected Ba/F3 cells with IL-3 completely prevented STI571-induced apoptosis
Source
Blood 2001 Apr 15;97(8):2440-8
Date of Entry
2001/05/22
Revision Date
2005/09/27
TEL-ARG fusion protein, human Preferred
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