MeSH Browser

MeSH Supplementary: ximelagatran
Unique ID: C426686
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C426686
Entry Term(s): Exanta; H 376 95; H 376-95; glycine, N-((1)1-cyclohexyl-2-((2)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester; glycine, N-((1R)1-cyclohexyl-2-((2S)-((((4-(amino(hydroxyimino)methyl)phenyl)methyl)amino)carbonyl)-1-azetidinyl)2-oxoethyl)-ethyl ester; xi-melagatran
Pharm Action: Antithrombins
Heading Mapped to: *Azetidines; *Benzylamines
Frequency: 388
Note: prodrug (via hydroxylation) of melagatran & a direct thrombin inhibitor; liver toxicity concerns so AZD0837 being developed to replace this
Source: Thromb Res 2001 Feb 1;101(3):171-81
Date of Entry: 2001/05/29
Revision Date: 2012/11/05

ximelagatran MeSH Supplementary Concept Data 2024