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hypocretin-2-saporin conjugate MeSH Supplementary Concept Data 2024


MeSH Supplementary
hypocretin-2-saporin conjugate
Unique ID
C435665
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C435665
Entry Term(s)
Hcrt2-SAP protein, chimeric
Registry Number
0
Previous Indexing
*NEUROPEPTIDES (2001-2002)
*PLANT PROTEINS (2001-2008)
*RIBOSOME INACTIVATING PROTEINS, TYPE 1 (2009-2018)
Heading Mapped to
*Saporins
*Neuropeptides
*Toxins, Biological
Frequency
10
Note
the endogenous ligand hypocretin-2/orexin B (Hcrt2)(C110858) conjugated to the ribosome-inactivating protein saporin (SAP); hypocretin-2-saporin lesions of the lateral hypothalamus produce narcoleptic-like sleep behavior in the rat
Source
J Neurosci 2001 Sep 15;21(18):7273-83
Date of Entry
2001/09/28
Revision Date
2018/09/24
hypocretin-2-saporin conjugate Preferred
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