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I-152 compound MeSH Supplementary Concept Data 2024


MeSH Supplementary
I-152 compound
Unique ID
C436346
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C436346
Entry Term(s)
NAC-MEA conjugate
Registry Number
0
Heading Mapped to
Acetylcysteine / *analogs & derivatives
Cysteamine / *analogs & derivatives
Frequency
6
Note
a prodrug of NAC (N-acetyl-L-cysteine) and MEA (cysteamine-2-mercaptoethylamine) with potent pro-GSH effects in human macrophages, astrocytes and lymphocytes; this molecule could be of interest in HIV infection in respect to its antioxidant and anti-HIV activities, but also in other diseases to counteract oxidative stress, that is, inflammation, cardiovascular diseases, and neurodegenerative diseases
Source
Bioorg Med Chem Lett 2001 May 7;11(9):1119-21
Date of Entry
2001/10/06
I-152 compound Preferred
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