MeSH Browser

MeSH Supplementary: MLL-AFX protein, human
Unique ID: C465587
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C465587
Registry Numbers: 0
Heading Mapped to: *Oncogene Proteins, Fusion; *Myeloid-Lymphoid Leukemia Protein
Frequency: 2
Note: MLL-AFX is a fusion gene created by t(X;11) chromosomal translocations in a subset of acute leukemias of either myeloid or lymphoid derivation; requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function
Source: Mol Cell Biol 2002 Sep;22(18);6542-52
Date of Entry: 2002/09/25
Revision Date: 2005/07/29

MLL-AFX protein, human MeSH Supplementary Concept Data 2025