MeSH Browser

MeSH Supplementary: peptide T1249
Unique ID: C474741
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C474741
Entry Term(s): T-1249 peptide; tifuvirtide
Registry Number: 0
Heading Mapped to: *Peptide Fragments; *HIV Envelope Protein gp41
Frequency: 28
Note: peptide derived from HR2 segment; gp41, intertwined heptad-repeat (HR2) regions form hydrophobic grooves that fold over and bind to corresponding HR1 coiled coils, collapsing gp41 into a stable six-helix or "trimer of hairpins" configuration; HIV fusion inhibitor
Source: J Am Chem Soc 2004 Nov 17;126(45):14758-63
Date of Entry: 2003/06/19
Revision Date: 2006/08/28

peptide T1249 MeSH Supplementary Concept Data 2024