MeSH Browser

MeSH Supplementary: tozasertib
Unique ID: C484810
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C484810
Entry Term(s): MK-0457; MK0457; N-(4-((4-(4-methylpiperazin-1-yl)-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)sulfanyl)phenyl)cyclopropanecarboxamide; N-(4-((4-(4-methylpiperazin-1-yl)-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)sulfanyl)phenyl)cyclopropanecarboxamide lactate; N-(4-((4-(4-methylpiperazin-1-yl)-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)sulfanyl)phenyl)cyclopropanecarboxamide, (2S)-2-hydroxypropanoate; VE 465; VE-465; VX-680; VX-680 lactate; VX680; VX680 lactate; cyclopropane carboxylic acid N-(4-(4-(4-methylpiperazin-1-yl)-6-(5-methyl-2H-pyrazol-3-ylamino)pyrimidin-2-ylsulfanyl)phenyl)amide; tozasertib lactate
Registry Number: 234335M86K
Related Numbers: CN8EF9N084
Heading Mapped to: *Cyclopropanes; *Piperazines; *Pyrazoles; *Pyrimidines
Frequency: 156
Note: a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth
Source: Nat Med 2004 Mar;10(3):262-7
Indexing Information: Protein Kinase Inhibitors
Date of Entry: 2004/05/06
Revision Date: 2022/05/31

tozasertib MeSH Supplementary Concept Data 2024