MeSH Browser

MeSH Supplementary: 8-acetyl-2-(2-(dimethylamino)ethyl)-1H-pyrimido(5,6,1-jk)carbazole-1,3(2H)-dione
Unique ID: C496386
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C496386
Entry Term(s): ER-37326
Registry Number: 0
Heading Mapped to: *Carbazoles; *Pyrimidines
Frequency: 1
Note: this compound inhibited the tumor growth of mouse sarcoma M5076 implanted into mice with T/C values of 42% and 13% at 3.13 and 6.25 mg/kg/d respectively without significantly affecting the body weight and increased the formation of DNA-topoisomerase II cross-linking in P388 cells
Source: Chem Pharm Bull (Tokyo). 2004 Sep;52(9):1071-81
Date of Entry: 2005/02/16

8-acetyl-2-(2-(dimethylamino)ethyl)-1H-pyrimido(5,6,1-jk)carbazole-1,3(2H)-dione MeSH Supplementary Concept Data 2024