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TIRAP protein, mouse MeSH Supplementary Concept Data 2025
an adapter protein involved in TLR-4 signal transduction in the inate immune response; acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, resulting in cytokine secretion and the inflammatory response; RefSeq NM_054096