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17,17'-bis(cyclopropylmethyl)-6,6',7,7'-tetrahydro-4,5-4',5'-diepoxy-6,6'-(benzylimino)(7,7'-bimorphinan)-3,3',14,14'-tetrol
MeSH Supplementary Concept Data 2024
Details
Concepts
MeSH Supplementary
17,17'-bis(cyclopropylmethyl)-6,6',7,7'-tetrahydro-4,5-4',5'-diepoxy-6,6'-(benzylimino)(7,7'-bimorphinan)-3,3',14,14'-tetrol
Unique ID
C499148
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C499148
Entry Term(s)
N-benzyl-norBNI
Registry Number
0
Heading Mapped to
Naltrexone
/
*analogs & derivatives
Frequency
2
Note
functions short-term as an MOR agonist and long-term as an KOR antagonist; structure in first source
Source
J Med Chem 2005 Mar 10;48(5):1676-9
Indexing Information
Receptors, Opioid, mu
Receptors, Opioid, kappa
Date of Entry
2005/04/10
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17,17'-bis(cyclopropylmethyl)-6,6',7,7'-tetrahydro-4,5-4',5'-diepoxy-6,6'-(benzylimino)(7,7'-bimorphinan)-3,3',14,14'-tetrol
Preferred
Concept UI
M0483061
Registry Number
0
Terms
17,17'-bis(cyclopropylmethyl)-6,6',7,7'-tetrahydro-4,5-4',5'-diepoxy-6,6'-(benzylimino)(7,7'-bimorphinan)-3,3',14,14'-tetrol
Preferred Term
Term UI
T635933
Date
04/10/2005
LexicalTag
NON
ThesaurusID
NLM (2005)
N-benzyl-norBNI
Term UI
T635934
Date
04/10/2005
LexicalTag
NON
ThesaurusID
NLM (2005)
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