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VX-944 MeSH Supplementary Concept Data 2024


MeSH Supplementary
VX-944
Unique ID
C504340
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C504340
Registry Number
0
Heading Mapped to
*Organic Chemicals
Frequency
1
Note
small molecule selective noncompetitive inhibitor of both isoforms of human inosine monophosphate dehydrogenase; induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway
Source
Oncogene 2005 Sep 1;24(38):5888-96
Indexing Information
IMP Dehydrogenase
Date of Entry
2005/10/05
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