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tecovirimat MeSH Supplementary Concept Data 2025


MeSH Supplementary
tecovirimat
Unique ID
C505045
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C505045
Entry Term(s)
4-trifluoromethyl-N-(3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop(f)isoindol-2(1H)-yl)-benzamide
N-((3aR,4R,4aR,5aS,6S,6aS)-1,3-Dioxo-3,3a,4,4a,5,5a,6,6a-octahydro-4,6-ethenocyclopropa(f)isoindol-2(1H)-yl)-4-(trifluoromethyl)benzamide
SIGA-246
ST 246
ST-246
TPOXX
benzamide, N-((3aR,4R,4aR,5aS,6S,6aS)-3,3a,4,4a,5,5a,6,6a-octahydro-1,3-dioxo-4,6-ethenocycloprop(F)isoindol-2(1H)-yl)-4-(trifluoromethyl)-, hydrate (1:1), rel-
tecovirimat monohydrate
Pharm Action
Antiviral Agents
Registry Numbers
F925RR824R
0
SB96YO2BR8
Related Numbers
SB96YO2BR8
Heading Mapped to
*Benzamides
*Phthalimides
Frequency
81
Note
A potent and specific inhibitor of orthopoxvirus replication. It is used for the treatment of SMALLPOX and other orthopoxvirus infections, including MONKEYPOX under expanded access investigational new drug protocol (https://www.cdc.gov/poxvirus/monkeypox/clinicians/Tecovirimat.html).
Source
J Virol 2005 Oct;79(20):13139-49
Date of Entry
2005/11/02
Revision Date
2022/08/05
tecovirimat Preferred
ST-246 Narrower
TPOXX Narrower
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