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OKT3xAntag2 MeSH Supplementary Concept Data 2025


MeSH Supplementary
OKT3xAntag2
Unique ID
C511762
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C511762
Registry Numbers
0
Heading Mapped to
*Antibodies, Bispecific
Frequency
1
Note
a bispecific molecule constructed by conjugating monoclonal antibody OKT3 (anti-CD3) with a bombesin/GRP antagonist (Antag2); mediates growth inhibition and apoptosis of small cell lung cancer cells by activated T cells through activation and cleavage of caspase-3 and poly(ADP-ribose) polymerase in vitro and in vivo
Source
Clin Cancer Res 2006 Apr 1;12(7 Pt 1):2224-31
Date of Entry
2006/07/17
Revision Date
2019/10/30
OKT3xAntag2 Preferred
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