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N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(4-(4-(2,3-dihydroxypropoxy)phenyl)butyl)guanidine MeSH Supplementary Concept Data 2025


MeSH Supplementary
N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(4-(4-(2,3-dihydroxypropoxy)phenyl)butyl)guanidine
Unique ID
C513153
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C513153
Entry Term(s)
DCC-DPBG compound
N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-(4-(2,3-dihydroxypropoxy)phenyl)butylguanidine
P552-02
Pharm Action
Sodium Channel Blockers
Registry Numbers
0
Heading Mapped to
*Guanidines
*Pyrazines
Frequency
3
Note
an epithelial sodium channel blocker for treating cystic fibrosis and chronic bronchitis; structure in first source
Source
J Med Chem 2006 Jul 13;49(14):4098-115
Date of Entry
2006/09/05
Revision Date
2018/09/24
N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-(4-(4-(2,3-dihydroxypropoxy)phenyl)butyl)guanidine Preferred
P552-02 Narrower
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