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1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone MeSH Supplementary Concept Data 2024


MeSH Supplementary
1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone
Unique ID
C517943
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C517943
Entry Term(s)
1-(4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone
G-1 cpd
G-1 ethanone compound
GPR30 agonist G1
Registry Number
0
Heading Mapped to
*Cyclopentanes
*Quinolines
Frequency
130
Note
G-1 was able to induce both c-fos expression and proliferation in the ERalpha-negative/GPR30-positive SKBR3 breast cancer cells, the requirement for ERalpha expression in GPR30/EGFR signaling may depend on the specific cellular context of different tumor types
Source
Cancer Res. 2007 Feb 15;67(4):1859-66
Date of Entry
2007/03/13
Revision Date
2024/01/30
1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone Preferred
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