MeSH Browser

MeSH Supplementary: CHIR-124
Unique ID: C518919
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C518919
Entry Term(s): ((S)-3-(1H-benzo(d)imidazol-2-yl)-6-chloro-4-quinuclidin-3-ylamino)quinolin-2(1H)-one
Registry Numbers: 0
Heading Mapped to: *Quinolines; *Quinuclidines
Frequency: 9
Note: a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo; structure in first source
Source: Clin Cancer Res 2007 Jan 15;13(2 Pt 1):591-602
Date of Entry: 2007/04/19
Revision Date: 1955/01/01

CHIR-124 MeSH Supplementary Concept Data 2025