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NVP-AST487 MeSH Supplementary Concept Data 2024


MeSH Supplementary
NVP-AST487
Unique ID
C522130
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C522130
Entry Term(s)
1-(4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)urea
AST 487
Registry Number
W34UO2M4T6
Heading Mapped to
*Phenylurea Compounds
*Pyrimidines
Frequency
4
Note
antineoplastic; a RET kinase inhibitor that blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells
Source
Cancer Res 2007 Jul 15;67(14):6956-64
Date of Entry
2007/08/20
Revision Date
2022/10/19
NVP-AST487 Preferred
1-(4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)urea Narrower
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