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EC0225 MeSH Supplementary Concept Data 2024


MeSH Supplementary
EC0225
Unique ID
C524636
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C524636
Registry Number
0
Heading Mapped to
*Folic Acid
Frequency
1
Note
a folate-targeted dual drug conjugate with antitumor activity; basically consists of subparts: folic acid; the hydrophilic peptide spacer, Asp-Asp-Asp-βDpr-Cys; the Vinca alkaloid drug moiety, DAVLBH; the DNA alkylating drug moiety, N7-mercaptoethyl-mitomycin C (N7-me-MMC); structure in first source
Source
Mol Pharm 2007 Sep-Oct;4(5):659-67
Date of Entry
2007/11/30
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