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(3aS-(3aalpha,4beta,5beta,7beta,7aalpha))-4-(octahydro-5-hydroxy-4,7-dimethyl-1,3-dioxo-4,7-epoxy-2H-isoindol-2-yl)-2-iodobenzonitrile MeSH Supplementary Concept Data 2025


MeSH Supplementary
(3aS-(3aalpha,4beta,5beta,7beta,7aalpha))-4-(octahydro-5-hydroxy-4,7-dimethyl-1,3-dioxo-4,7-epoxy-2H-isoindol-2-yl)-2-iodobenzonitrile
Unique ID
C529326
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C529326
Entry Term(s)
OHDDEII cpd
Registry Numbers
0
Heading Mapped to
*Bridged Bicyclo Compounds, Heterocyclic
*Isoindoles
Frequency
1
Note
has potent in vivo efficacy after oral dosing in the CWR22 human prostate tumor xenograph model; structure in first source
Source
Bioorg Med Chem Lett 2008 Mar 15;18(6):1910-5
Date of Entry
2008/06/04
Revision Date
1955/01/01
(3aS-(3aalpha,4beta,5beta,7beta,7aalpha))-4-(octahydro-5-hydroxy-4,7-dimethyl-1,3-dioxo-4,7-epoxy-2H-isoindol-2-yl)-2-iodobenzonitrile Preferred
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