MeSH Browser

MeSH Supplementary: Renal cysts and diabetes syndrome
Unique ID: C535520
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C535520
Entry Term(s): Glomerulocystic kidney disease, hypoplastic type; Glomerulocystic kidney, familial hypoplastic; Hyperuricemic nephropathy, familial juvenile, atypical; Maturity-onset diabetes of the young, type 5
Heading Mapped to: *Central Nervous System Diseases; Dental Enamel / abnormalities; *Diabetes Mellitus, Type 2; *Kidney Diseases, Cystic
Frequency: 36
Note: An autosomal dominant disorder comprising (1) nondiabetic renal disease resulting from abnormal renal development, and (2) diabetes, which in some cases occurs earlier than age 25 years and is thus consistent with a diagnosis of maturity-onset diabetes of the young (MODY). The renal disease is highly variable and includes renal cysts, glomerular tufts, aberrant nephrogenesis, primitive tubules, irregular collecting systems, oligomeganephronia, enlarged RENAL PELVIS, abnormal calyces, small kidney, single kidney, FUSED KIDNEY, and hyperuricemic nephropathy. Affected individuals may also have abnormalities of the genital tract, including vaginal aplasia, rudimentary uterus, bicornuate uterus, epididymal cysts, and atresia of the vas deferens. Mutations in the HNF1B gene have been identified. OMIM: 137920
Date of Entry: 2010/08/25
Revision Date: 2015/09/27

Renal cysts and diabetes syndrome MeSH Supplementary Concept Data 2024