MeSH Browser

MeSH Supplementary: Chromosome 1, monosomy 1p
Unique ID: C535591
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C535591
Entry Term(s): Deletion 1p; Monosomy 1p
Registry Numbers: 0
Heading Mapped to: *Chromosome Deletion; Chromosomes, Human, Pair 1
Frequency: 39
Note: Deletion of a portion of the p region of Crhomosome 1. Monosomy 1p36 (OMIM: 607872) is the most common terminal deltion syndrome in humans, occuring in 1 in 5000 births. It causes severe craniofacial abnormalities and developmental disabilities, including delayed growth, CRANIOSYNOSTOSES; MICROCEPHALY; CLEFT PALATE; eye and ear defects; congenital heart defects, seizures, and intellectual disability.
Date of Entry: 2010/08/25
Revision Date: 2016/09/29

Chromosome 1, monosomy 1p MeSH Supplementary Concept Data 2025