MeSH Browser

MeSH Supplementary: Intrahepatic Cholestasis of Pregnancy
Unique ID: C535932
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C535932
Entry Term(s): Cholestasis, Intrahepatic, Of Pregnancy; Cholestasis, Pregnancy-Related; Cholestasis, intrahepatic of pregnancy; Familial intrahepatic cholestasis of pregnancy; Familial recurrent intrahepatic cholestasis of pregnancy; Obstetric Cholestasis; Pregnancy related cholestasis; Pregnancy-Related Cholestasis; Recurrent intrahepatic cholestasis of pregnancy
Heading Mapped to: *Cholestasis, Intrahepatic; *Pregnancy Complications
Frequency: 493
Note: A reversible form of cholestasis that typically occurs in the third trimester of pregnancy and frequently recurs in subsequent pregnancies. Patients present with PRURITIS; JAUNDICE increased serum bile salts, and abnormal liver enzyme levels. Symptoms resolve soon after delivery; some patients with may also be susceptible to oral contraceptive-induced cholestasis. Fetal complications may occur, including PLACENTAL INSUFFICIENCY; PREMATURE LABOR; FETAL DISTRESS, and intrauterine death . A heterozygous mutation in the ATP8B1 gene has been identified. OMIM: 147480
Date of Entry: 2010/08/25
Revision Date: 2015/08/18

Intrahepatic Cholestasis of Pregnancy MeSH Supplementary Concept Data 2024