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Intrahepatic Cholestasis of Pregnancy MeSH Supplementary Concept Data 2023


MeSH Supplementary
Intrahepatic Cholestasis of Pregnancy
Unique ID
C535932
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C535932
Entry Term(s)
Cholestasis, Intrahepatic, Of Pregnancy
Cholestasis, Pregnancy-Related
Cholestasis, intrahepatic of pregnancy
Familial intrahepatic cholestasis of pregnancy
Familial recurrent intrahepatic cholestasis of pregnancy
Obstetric Cholestasis
Pregnancy related cholestasis
Pregnancy-Related Cholestasis
Recurrent intrahepatic cholestasis of pregnancy
Registry Number
0
Heading Mapped to
*Cholestasis, Intrahepatic
*Pregnancy Complications
Frequency
491
Note
A reversible form of cholestasis that typically occurs in the third trimester of pregnancy and frequently recurs in subsequent pregnancies. Patients present with PRURITIS; JAUNDICE increased serum bile salts, and abnormal liver enzyme levels. Symptoms resolve soon after delivery; some patients with may also be susceptible to oral contraceptive-induced cholestasis. Fetal complications may occur, including PLACENTAL INSUFFICIENCY; PREMATURE LABOR; FETAL DISTRESS, and intrauterine death . A heterozygous mutation in the ATP8B1 gene has been identified. OMIM: 147480
Date of Entry
2010/08/25
Revision Date
2015/08/18
Intrahepatic Cholestasis of Pregnancy Preferred
Familial intrahepatic cholestasis of pregnancy Narrower
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