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Sacral defect and anterior sacral meningocele MeSH Supplementary Concept Data 2025


MeSH Supplementary
Sacral defect and anterior sacral meningocele
Unique ID
C537221
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C537221
Entry Term(s)
Agenesis of sacrum
Caudal Dysgenesis Syndrome
Hypoplasia of sacrum
Lumbosacral agenesis
Sacral Defect with Anterior Meningocele
Sacral agenesis
Sacral defect anterior meningocele
Registry Numbers
0
Heading Mapped to
*Abnormalities, Multiple
*Meningocele
Sacrococcygeal Region / abnormalities
Frequency
67
Note
A hereditary autosomal dominant form of caudal dysgenesis that is present at birth and becomes symptomatic later in life due to obstructive labor in females, chronic CONSTIPATION, or MENINGITIS. Caudal dysgenesis syndrome and caudal regression syndrome broadly refer to a range of congenital caudal anomalies affecting the caudal SPINE and SPINAL CORD, the hindgut, the UROGENITAL SYSTEM, and the lower limbs. Approximately 15 to 25% of mothers of children with caudal dysgenesis have TYPE I DIABETES MELLITUS. A mutation in the VANGL1 gene has been identified in some cases of caudal regression. OMIM: 600145
Date of Entry
2010/08/25
Revision Date
2015/08/18
Sacral defect and anterior sacral meningocele Preferred
Sacral agenesis Related
Lumbosacral agenesis Related
Caudal Dysgenesis Syndrome Related
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