MeSH Browser

MeSH Supplementary: Sacral defect and anterior sacral meningocele
Unique ID: C537221
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C537221
Entry Term(s): Agenesis of sacrum; Caudal Dysgenesis Syndrome; Hypoplasia of sacrum; Lumbosacral agenesis; Sacral Defect with Anterior Meningocele; Sacral agenesis; Sacral defect anterior meningocele
Registry Number: 0
Heading Mapped to: *Abnormalities, Multiple; *Meningocele; Sacrococcygeal Region / *abnormalities
Frequency: 67
Note: A hereditary autosomal dominant form of caudal dysgenesis that is present at birth and becomes symptomatic later in life due to obstructive labor in females, chronic CONSTIPATION, or MENINGITIS. Caudal dysgenesis syndrome and caudal regression syndrome broadly refer to a range of congenital caudal anomalies affecting the caudal SPINE and SPINAL CORD, the hindgut, the UROGENITAL SYSTEM, and the lower limbs. Approximately 15 to 25% of mothers of children with caudal dysgenesis have TYPE I DIABETES MELLITUS. A mutation in the VANGL1 gene has been identified in some cases of caudal regression. OMIM: 600145
Date of Entry: 2010/08/25
Revision Date: 2015/08/18

Sacral defect and anterior sacral meningocele MeSH Supplementary Concept Data 2024