MeSH Browser

MeSH Supplementary: Heterotaxy, visceral, X-linked
Unique ID: C538116
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C538116
Entry Term(s): Dextrocardia with other cardiac malformations; Heterotaxy, Visceral, 1, X-Linked; Heterotaxy, Visceral, 5, Autosomal; Laterality, X-linked; Situs inversus, complex cardiac defects, and splenic defects, X-linked; Visceral heterotaxia
Registry Numbers: 0
Heading Mapped to: *Dextrocardia; *Genetic Diseases, X-Linked; *Heterotaxy Syndrome
Frequency: 57
Note: A clinically and genetically heterogeneous developmental condition where visceral organs (heart, lungs, liver, spleen, and stomach) are oriented randomly with respect to each other and the left-right axis. CONGENITAL HEART DEFECTS and ARRYTHMIAS are common in affected individuals. The X-linked form is caused by mutations in the ZIC3 gene (OMIM: 306955). The autosomal 5 form is dominant and is caused by mutations in the NODAL gene. OMIM: 270100
Date of Entry: 2010/08/25
Revision Date: 2015/08/18

Heterotaxy, visceral, X-linked MeSH Supplementary Concept Data 2025