MeSH Browser

MeSH Supplementary: ivacaftor
Unique ID: C545203
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C545203
Entry Term(s): 3-quinolinecarboxamide, N-(2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-1,4-dihydro-4-oxo-; Kalydeco; N-(2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide; N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide; VX-770
Pharm Action: Chloride Channel Agonists
Registry Numbers: 1Y740ILL1Z; 0
Heading Mapped to: *Aminophenols; *Quinolones
Frequency: 672
Note: a CFTR potentiator; structure in first source
Source: Proc Natl Acad Sci U S A 2009 Nov 3;106(44):18825-30
Indexing Information: Cystic Fibrosis Transmembrane Conductance Regulator
Date of Entry: 2009/11/30
Revision Date: 2016/10/31

ivacaftor MeSH Supplementary Concept Data 2025