The most common tumor of the human PAROTID GLAND. It is a benign, slow-growing tumor, but local recurrences are observed. It can be caused by t(3;8)(p21;q12) translocations that result in a fusion between pleomorphic adenoma gene-1 (PLAG1) and the beta-1-catenin gene (CTNNB1) and the TCEA1 gene. OMIM: 181030