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Diabetes Mellitus, Permanent Neonatal MeSH Supplementary Concept Data 2023

MeSH Supplementary
Diabetes Mellitus, Permanent Neonatal
Unique ID
RDF Unique Identifier
Entry Term(s)
Diabetes Mellitus, Permanent, of Infancy
Permanent Neonatal Diabetes Mellitus
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Heading Mapped to
*Diabetes Mellitus
A rare autosomal dominant genetically heterogeneous hereditary form of diabetes mellitus which is distinct from Type I diabetes mellitus and affected individuals present with insulin-requiring hyperglycemia within the first 3 months of life. About 50% of cases resolve by 3 months but may later develop type II diabetes. The cases that do not resolve develop permanent insulin-dependent diabetes and many also have neurologic and morphologic abnormalities. Mutations in the GCK, KCNJ11, ABCC8, and INS genes have been identified. OMIM: 606176
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Diabetes Mellitus, Permanent Neonatal Preferred
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