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Immune Deficiency Disease MeSH Supplementary Concept Data 2025
A deficiency of both HUMORAL IMMUNITY and CELLULAR IMMUNITY, with a severe deficiency of IMMUNOGLOBULIN M. Patients cannot contain VIRAL INFECTIONS or BACTERIAL INFECTIONS, especially those caused by encapsulated extracellular pathogens such as STREPTOCOCCUS PNEUMONIAE. SEPSIS frequently occurs and patients also exhibit a defective response to primary IMMUNIZATION. OMIM: 242850