MeSH Browser

MeSH Supplementary: Parkinson Disease, Familial, Type 1
Unique ID: C566823
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C566823
Entry Term(s): Atypical Parkinson Disease; Lewy Body Parkinsonism; Parkinson Disease, Autosomal Dominant
Registry Number: 0
Heading Mapped to: *Parkinson Disease
Frequency: 48
Note: A severe hereditary autosomal dominant form of Parkinson Disease with onset in mid to late adulthood. It is characterized by the presence of LEWY BODIES in the SUBSTANTIA NIGRA and LOCUS CERULEUS, cell loss and GLIOSIS in the brainstem, and tissue vacuolization in the medial temporal regions. Mutations in the SNCA gene have been identified. OMIM: 168601
Date of Entry: 2012/08/24
Revision Date: 2015/09/27

Parkinson Disease, Familial, Type 1 MeSH Supplementary Concept Data 2024