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1-(4-(5'-chloro-3,5-dimethyl-2,4'-bipyridin-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one MeSH Supplementary Concept Data 2025


MeSH Supplementary
1-(4-(5'-chloro-3,5-dimethyl-2,4'-bipyridin-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one
Unique ID
C573117
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C573117
Entry Term(s)
PF-5274857
Registry Numbers
0
Heading Mapped to
*Piperazines
2,2'-Dipyridyl / analogs & derivatives
Frequency
2
Note
a potent and selective Smoothened antagonist that penetrates the blood-brain barrier; structure in first source
Source
Mol Cancer Ther. 2012 Jan;11(1):57-65
Date of Entry
2012/06/28
Revision Date
2012/06/28
1-(4-(5'-chloro-3,5-dimethyl-2,4'-bipyridin-2'-yl)piperazin-1-yl)-3-(methylsulfonyl)propan-1-one Preferred
PF-5274857 Narrower
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