MeSH Browser

MeSH Supplementary: agerafenib
Unique ID: C575620
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C575620
Entry Term(s): 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea; 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride; CEP-32496; RXDX-105
Pharm Action: Protein Kinase Inhibitors
Registry Number: 78I4VEX88N
Heading Mapped to: *Phenylurea Compounds; *Quinazolines
Frequency: 6
Note: inhibitor of RAF family kinases; structure in first source
Source: J Med Chem. 2012 Feb 9;55(3):1082-105.
Indexing Information: Proto-Oncogene Proteins B-raf
Date of Entry: 2012/10/14
Revision Date: 2020/06/17

agerafenib MeSH Supplementary Concept Data 2024