MeSH Browser

MeSH Supplementary: venetoclax
Unique ID: C579720
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/C579720
Entry Term(s): 4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide; ABT-199; GDC-0199; RG-7601; RG7601; Venclexta; benzamide, 4-(4-((2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-n-((3-nitro-4-(((tetrahydro-2h-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-2-(1h-pyrrolo(2,3-b)pyridin-5-yloxy)-
Pharm Action: Antineoplastic Agents
Heading Mapped to: *Sulfonamides; *Bridged Bicyclo Compounds, Heterocyclic
Frequency: 1222
Note: A BCL-2 inhibitor with antineoplastic activity that is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA associated with chromosome 17p deletion; structure in first source.
Source: Nat Med. 2013 Feb;19(2):202-8.
Date of Entry: 2013/04/14
Revision Date: 2016/10/06

venetoclax MeSH Supplementary Concept Data 2024