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venetoclax MeSH Supplementary Concept Data 2022


MeSH Supplementary
venetoclax
Unique ID
C579720
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C579720
Entry Term(s)
4-(4-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-((tetrahydro-2H-pyran-4-ylmethyl)amino)phenyl)sulfonyl)-2-(1H-pyrrolo(2,3-b)pyridin-5-yloxy)benzamide
ABT-199
GDC-0199
RG-7601
RG7601
Venclexta
benzamide, 4-(4-((2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-n-((3-nitro-4-(((tetrahydro-2h-pyran-4-yl)methyl)amino)phenyl)sulfonyl)-2-(1h-pyrrolo(2,3-b)pyridin-5-yloxy)-
Pharm Action
Antineoplastic Agents
Registry Number
N54AIC43PW
Heading Mapped to
*Sulfonamides
*Bridged Bicyclo Compounds, Heterocyclic
Frequency
964
Note
A BCL-2 inhibitor with antineoplastic activity that is used in the treatment of CHRONIC LYMPHOCYTIC LEUKEMIA associated with chromosome 17p deletion; structure in first source.
Source
Nat Med. 2013 Feb;19(2):202-8.
Date of Entry
2013/04/14
Revision Date
2016/10/06
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