MeSH Browser

MeSH Heading: Heparanase
Tree Number(s): D08.811.277.450.426.001
Unique ID: D000099175
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000099175
Scope Note: A mammalian endoglucuronidase which degrades HEPARAN SULFATE glycosaminoglycans into short 5-6 kDa pieces.
Entry Term(s): Heparan Sulfate Endoglycosidase; Heparan Sulphate Endoglycosidase
Registry Numbers: EC 3.2.1.-
Public MeSH Note: 2026; HEPARANASE was indexed under GLUCURONIDASE 2005-2025 and under GLYCOSIDE HYDROLASES 1983-2004
History Note: 2026 (1983)
Date Introduced: 2026/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Heparanase MeSH Descriptor Data 2026