A histone deacetylase that catalyzes the deacetylation of the core HISTONES (H2A, H2B,H3, and H4) as well as other cellular proteins. It functions in the CELL NUCLEUS as part of the nuclear-receptor corepressor complex to regulate the GENETIC TRANSCRIPTION of NUCLEAR RECEPTORS.
Entry Term(s)
HDAC3 Enzyme
Registry Numbers
EC 3.5.1.98
Public MeSH Note
2026; HISTONE DEACETYLASE 3 was indexed under HISTONE DEACETYLASES 2001-2025
A histone deacetylase that catalyzes the deacetylation of the core HISTONES (H2A, H2B,H3, and H4) as well as other cellular proteins. It functions in the CELL NUCLEUS as part of the nuclear-receptor corepressor complex to regulate the GENETIC TRANSCRIPTION of NUCLEAR RECEPTORS.
