MeSH Browser

MeSH Heading: p300-CBP-Associated Factor
Tree Number(s): D08.811.913.050.134.415.500.575.601; D12.776.930.680.601
Unique ID: D000099224
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000099224
Scope Note: A p300-CBP transcription factor with intrinsic HISTONE ACETYLASE activity that functions to promote TRANSCRIPTIONAL ACTIVATION. Among its functions is suppression of the CELL CYCLE where it competes with ADENOVIRUS E1A PROTEINS.
Entry Term(s): Histone Acetylase p300; PCAF Acetylase; PCAF Histone Acetylase; p300 Acetyltransferase; p300-CREB-Binding Protein-Associated Factor
Registry Numbers: EC 2.3.1.48
Public MeSH Note: 2026; was indexed under P300-CBP TRANSCRIPTION FACTORS 2008-2025 and under CELL CYCLE PROTEINS; HISTONE ACETYLTRANSFERASES; TRANSCRIPTION FACTORS 2006-2007 and under ACETYLTRANSFERASES 1996-2005
History Note: 2026 (1996)
Date Introduced: 2026/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000768988
Registry Numbers: EC 2.3.1.48
Scope Note: A p300-CBP transcription factor with intrinsic HISTONE ACETYLASE activity that functions to promote TRANSCRIPTIONAL ACTIVATION. Among its functions is suppression of the CELL CYCLE where it competes with ADENOVIRUS E1A PROTEINS.
Terms: p300-CBP-Associated Factor Preferred Term
Term UI T001148291
Date04/29/2025
LexicalTag NON
ThesaurusID NLM (2026); Histone Acetylase p300
Term UI T001148297
Date04/29/2025
LexicalTag NON
ThesaurusID NLM (2026); p300 Acetyltransferase
Term UI T001148298
Date04/29/2025
LexicalTag NON
ThesaurusID NLM (2026); p300-CREB-Binding Protein-Associated Factor
Term UI T001148294
Date04/29/2025
LexicalTag NON
ThesaurusID NLM (2026); PCAF Acetylase
Term UI T001148295
Date04/29/2025
LexicalTag NON
ThesaurusID NLM (2026); PCAF Histone Acetylase
Term UI T001148296
Date04/29/2025
LexicalTag NON
ThesaurusID NLM (2026)

p300-CBP-Associated Factor MeSH Descriptor Data 2026