MeSH Browser

MeSH Heading: Cystic Fibrosis
Tree Number(s): C06.689.202; C08.381.187; C16.320.190; C16.614.213
Unique ID: D003550
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D003550
Annotation: a specific disease entity: do not use for fibrocystic states of various organs
Scope Note: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Entry Term(s): Cystic Fibrosis of Pancreas; Fibrocystic Disease of Pancreas; Mucoviscidosis; Pancreatic Cystic Fibrosis; Pulmonary Cystic Fibrosis
See Also: Cystic Fibrosis Transmembrane Conductance Regulator; Mice, Inbred CFTR
Public MeSH Note: 67; was PANCREATIC CYSTIC FIBROSIS 1963-66
Online Note: use CYSTIC FIBROSIS to search PANCREATIC CYSTIC FIBROSIS 1966
History Note: 67; was PANCREATIC CYSTIC FIBROSIS 1963-66
Date Established: 1967/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

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surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Cystic Fibrosis MeSH Descriptor Data 2024