subheading only: includes "binding", "catabolism", "conversion", "degradation", "pathway", "splitting", "storage", "utilization"; not for "anabolism": use instead /biosynthesis; for "absorption", "release", "transport", "uptake" /pharmacokinetics is also available; for excretion into the blood use /blood, into the cerebrospinal fluid use /cerebrospinal fluid, into the urine use /urine; for biosynthesis or synthesis use /biosynthesis; for metabolic aspects of enzymes use /enzymology with Category A, B, and C terms
Scope Note
Used with organs, cells and subcellular fractions, organisms, and diseases for biochemical changes. It is used also with drugs and chemicals for catabolic changes (breakdown of complex molecules into simpler ones). For anabolic processes (conversion of small molecules into large), BIOSYNTHESIS is used. For enzymology and pharmacokinetics use the specific subheadings.
Entry Version
METAB
Abbreviation
ME
Entry Term(s)
biochemical pathways
biodegradation
biotransformation
catabolism
degradation
secretion
Online Note
search policy: Online Manual; use; main heading/ME or ME (SH) or SUBS APPLY ME; included /pharmacokinetics 1966-87
Used with organs, cells and subcellular fractions, organisms, and diseases for biochemical changes. It is used also with drugs and chemicals for catabolic changes (breakdown of complex molecules into simpler ones). For anabolic processes (conversion of small molecules into large), BIOSYNTHESIS is used. For enzymology and pharmacokinetics use the specific subheadings.
Used for the discharge across the cell membrane, into the extracellular space or ducts, of endogenous substances resulting from the activity of intact cells of glands, tissues, or organs.
