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Alu Elements MeSH Descriptor Data 2024


MeSH Heading
Alu Elements
Tree Number(s)
G02.111.570.080.708.330.800.800.050
G05.360.080.708.330.800.800.050
G05.360.340.024.425.800.800.050
Unique ID
D020087
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020087
Scope Note
The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
Entry Term(s)
Alu Family
Alu Repetitive Sequences
Alu-Like Repetitive Sequence
Previous Indexing
Repetitive Sequences, Nucleic Acid (1981-1998)
See Also
Mutagenesis, Insertional
Public MeSH Note
99; see REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE see REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98
History Note
99; use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-98
Date Established
1999/01/01
Date of Entry
1998/06/10
Revision Date
2008/07/08
Alu Elements Preferred
Alu-Like Repetitive Sequence Related
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