MeSH Browser

MeSH Heading: Alu Elements
Tree Number(s): G02.111.570.080.708.330.800.800.050; G05.360.080.708.330.800.800.050; G05.360.340.024.425.800.800.050
Unique ID: D020087
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020087
Scope Note: The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
Entry Term(s): Alu Family; Alu Repetitive Sequences; Alu-Like Repetitive Sequence
Previous Indexing: Repetitive Sequences, Nucleic Acid (1981-1998)
See Also: Mutagenesis, Insertional
Public MeSH Note: 1999; see REPETITIVE SEQUENCES, NUCLEIC ACID 1988-1998; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE see REPETITIVE SEQUENCES, NUCLEIC ACID 1988-1998
History Note: 1999; use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-1998; for ALU REPETITIVE SEQUENCE, ALU FAMILY, and ALU-LIKE REPETITIVE SEQUENCE use REPETITIVE SEQUENCES, NUCLEIC ACID 1988-1998
Date Established: 1999/01/01
Date of Entry: 2024/08/09
Revision Date: 2024/05/23

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0029813
Scope Note: The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). It is derived from the 7SL RNA component of the SIGNAL RECOGNITION PARTICLE and contains an RNA polymerase III promoter. Transposition of this element into coding and regulatory regions of genes is responsible for many heritable diseases.
Terms: Alu Elements Preferred Term
Term UI T059819
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1999); Alu Family
Term UI T059817
Date03/24/1998
LexicalTag NON
ThesaurusID NLM (1999); Alu Repetitive Sequences
Term UI T059818
Date11/25/1997
LexicalTag NON
ThesaurusID NLM (1999)

Alu Elements MeSH Descriptor Data 2025