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Cerebroside-Sulfatase MeSH Descriptor Data 2024


MeSH Heading
Cerebroside-Sulfatase
Tree Number(s)
D08.811.277.352.827.070.250
Unique ID
D002553
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002553
Annotation
/defic: consider also LEUKODYSTROPHY, METACHROMATIC
Scope Note
An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.
Entry Term(s)
Arylsulfatase A
Sulfatidate Sulfatase
Registry Numbers
EC 3.1.6.8
CAS Type 1 Name
Cerebroside-3-sulfate 3-sulfohydrolase
Previous Indexing
Arylsulfatases (1975)
Sulfatases (1972-1974)
See Also
Leukodystrophy, Metachromatic
Public MeSH Note
87; was see under SULFATASES 1976-86
History Note
87(76); was see under SULFATASES 1976-86
Date Established
1987/01/01
Date of Entry
1975/07/25
Revision Date
2003/07/09
Cerebroside-Sulfatase Preferred
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