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A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The binding of calcium ions to this protein allows this protein to bind to cyclic nucleotide phosphodiesterases and to adenyl cyclase with subsequent activation. Thereby this protein modulates cyclic AMP and cyclic GMP levels.
Entry Term(s)
Bovine Activator Protein
Calcium-Dependent Activator Protein
Calcium-Dependent Regulator
Cyclic AMP-Phosphodiesterase Activator
Phosphodiesterase Activating Factor
Phosphodiesterase Activator Protein
Phosphodiesterase Protein Activator
Regulator, Calcium-Dependent
Registry Numbers
0
NLM Classification #
QU 55.2
Previous Indexing
Calcium (1966-1978)
Carrier Proteins (1971-1978)
Enzyme Activation (1969-1978)
Public MeSH Note
84; was CALCIUM-DEPENDENT REGULATOR see under CALCIUM-BINDING PROTEINS 1980-83; was CALCIUM-DEPENDENT REGULATOR see under CARRIER PROTEINS 1979
Online Note
use CALMODULIN to search CALCIUM-DEPENDENT REGULATOR 1979-83
History Note
84; was CALCIUM-DEPENDENT REGULATOR see under CALCIUM-BINDING PROTEINS 1980-83; was CALCIUM-DEPENDENT REGULATOR see under CARRIER PROTEINS 1979
A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The binding of calcium ions to this protein allows this protein to bind to cyclic nucleotide phosphodiesterases and to adenyl cyclase with subsequent activation. Thereby this protein modulates cyclic AMP and cyclic GMP levels.